Rhegmatogenous retinal detachment following focal retinal necrosis in endogenous endophthalmitis due to methicillin-resistant Staphylococcus aureus septicemia.

Endogenous endophthalmitis leading to rhegmatogenous retinal detachment is one of the vision-threatening, devastating sequelae. Risk factors usually include a systemic focus of infection and conditions causing immunosuppression (diabetes, prostheses, and intravenous drug use). The most commonly implicated pathogens are Gram-positive coagulase-negative ones, especially Staphylococcus epidermidis. Cases of methicillin-resistant Staphylococcus aureus (MRSA) septicemia causing endogenous endophthalmitis have been reported with poor visual outcomes even with aggressive treatment. We hereby report a case of MRSA septicemia presenting with focal chorioretinal necrosis progressing to rhegmatogenous retinal detachment in a young postpartum female patient, which was successfully managed with vitrectomy.