Congenital cystic eye and coloboma with a cyst hybrid phenotype: a developmental continuum.

A 2-day-old boy presented with a large orbital mass, which showed radiological and pathological overlap between congenital cystic eye (CCE) and coloboma with cyst (CwC). Initially identified on prenatal imaging at 21 weeks, the patient underwent postnatal clinical and radiologic evaluation followed by histopathologic analysis of the enucleated eye. The coexistence of both anomalies within a single globe challenges the traditional view of CCE and CwC as distinct entities and supports a unifying theory of a developmental spectrum of early ocular malformations.