JACC. Case reports · 2025
Infective Endocarditis 19 Months After Transcatheter Ostium Secundum Atrial Septal Defect Closure in a 6-Year-Old.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gery Camille, Leborgne Anne Sophie, Albenque Grégoire, Lourtet-Hascoet Julie, Batteux Clément, Roussin Régine, Hascoet Sébastien
Аннотация
BACKGROUND: Infective endocarditis (IE) after transcatheter atrial septal defect (ASD) closure is rare.
CASE SUMMARY: We report the case of a 6-year-old girl who developed methicillin-resistant Staphylococcus aureus IE 19 months after ASD closure with an Amplatzer device. She presented with severe sepsis, a large vegetation on the right atrial side of the occluder, and moderate tricuspid regurgitation. Despite empirical antibiotic therapy, persistent bacteremia mandated surgical removal of the device, ASD closure with a pericardial patch, and tricuspid valve repair. Six weeks of targeted antibiotics led to a favorable 1-year outcome.
DISCUSSION: This case, alongside other reports of late-onset IE after transcatheter ASD closure, highlights that although rare, such infections can occur well beyond 6 months postprocedure. This observation questions current guidelines restricting prophylactic measures to the early postimplant period.
TAKE-HOME MESSAGE: Patients with septal occluders may require prolonged vigilance and reinforced education on skin and dental hygiene to minimize the risk of late IE.
CASE SUMMARY: We report the case of a 6-year-old girl who developed methicillin-resistant Staphylococcus aureus IE 19 months after ASD closure with an Amplatzer device. She presented with severe sepsis, a large vegetation on the right atrial side of the occluder, and moderate tricuspid regurgitation. Despite empirical antibiotic therapy, persistent bacteremia mandated surgical removal of the device, ASD closure with a pericardial patch, and tricuspid valve repair. Six weeks of targeted antibiotics led to a favorable 1-year outcome.
DISCUSSION: This case, alongside other reports of late-onset IE after transcatheter ASD closure, highlights that although rare, such infections can occur well beyond 6 months postprocedure. This observation questions current guidelines restricting prophylactic measures to the early postimplant period.
TAKE-HOME MESSAGE: Patients with septal occluders may require prolonged vigilance and reinforced education on skin and dental hygiene to minimize the risk of late IE.