JACC. Case reports · 2026
Clostridium perfringens Infective Endocarditis: Revisiting a Forgotten Pathogen.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Rubin Jake, Eisenberg Scott, Gold Matthew, Deng Nikita, Shikhare Anuja, Patel Shree, Kumar Sakthi, Lateef Almeera, Mehta Puja, Sperling Laurence
Аннотация
BACKGROUND: Clostridium perfringens is a rare cause of infective endocarditis (IE), with only a limited number of cases reported in the literature.
CASE SUMMARY: A 57-year-old man with complex congenital heart disease, including a surgically repaired double-outlet right ventricle and prior pulmonic valve replacement, presented with recurrent fevers and Cperfringens bacteremia. Although transthoracic echocardiography revealed no acute disease, cardiac computed tomography identified a vegetation adherent to the ventricular septal defect patch, an atypical and previously unreported site for this organism. The patient underwent successful treatment with prolonged intravenous penicillin without surgical intervention.
DISCUSSION: Standard echocardiography is limited in the detection of vegetations in repaired congenital heart disease, underscoring the importance of advanced multimodality imaging.
TAKE-HOME MESSAGES: Based on computed tomography-supported findings of IE, the patient underwent successful treatment with prolonged intravenous penicillin without surgical intervention. This case adds to the limited literature on Cperfringens as a rare cause of IE and highlights the importance of individualized, multidisciplinary management in complex congenital heart disease.
CASE SUMMARY: A 57-year-old man with complex congenital heart disease, including a surgically repaired double-outlet right ventricle and prior pulmonic valve replacement, presented with recurrent fevers and Cperfringens bacteremia. Although transthoracic echocardiography revealed no acute disease, cardiac computed tomography identified a vegetation adherent to the ventricular septal defect patch, an atypical and previously unreported site for this organism. The patient underwent successful treatment with prolonged intravenous penicillin without surgical intervention.
DISCUSSION: Standard echocardiography is limited in the detection of vegetations in repaired congenital heart disease, underscoring the importance of advanced multimodality imaging.
TAKE-HOME MESSAGES: Based on computed tomography-supported findings of IE, the patient underwent successful treatment with prolonged intravenous penicillin without surgical intervention. This case adds to the limited literature on Cperfringens as a rare cause of IE and highlights the importance of individualized, multidisciplinary management in complex congenital heart disease.