The association between polyhydramnios and the risk of placenta abruption: a meta-analysis.

Background

The results of studies about the effect of polyhydramnios on the risk of placental abruption are a controversy. This study was conducted to determine the association between polyhydramnios and the risk of placental abruption.

Methods

PubMed, Scopus, and Web of Science were searched in September 2017 along with references from meta-analyses and reviews. We assessed publication bias using the rank correlation test (Begg's test) and the regression asymmetry test (Egger's test). The studies' heterogeneity was measured by the Q-statistic and I-squared (I2) tests. The random-effects model was conducted to obtain pooled odds ratio (OR) as a measure of the association between polyhydramnios and the risk of placental abruption.

Results

A total of 10 studies were included in this meta-analysis with a sample of 198,359 participants. There was a significant association between polyhydramnios and the risk of placental abruption [OR: 1.93 (95% CI: 1.23-2.63)].

Conclusions

The present study is the first meta-analysis that reported polyhydramnios is a risk factor for placental abruption.