European journal of obstetrics, gynecology, and reproductive biology · 2012
Effect of delayed umbilical cord clamping on blood gas analysis.
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Valero Javier, Desantes Domingo, Perales-Puchalt Alfredo, Rubio Juan, Diago Almela Vicente J, Perales Alfredo
Аннотация
OBJECTIVE: To ascertain if there are differences in umbilical cord blood gas analysis between immediate and delayed cord clamping.
STUDY DESIGN: In a prospective observational study on 60 vaginally delivered healthy term newborns, we sampled umbilical cord blood immediately after delivery and at the time umbilical cord pulsation spontaneously ceased.
RESULTS: There were significant decreases in pH, oxygen saturation (sO(2)), glycemia, oxygen content (ctO(2)), bicarbonate (HCO(3)(-)) and base excess (BE). Lactate and [Formula: see text] increased. Delayed cord clamping pH correlated with immediate cord clamping pH, [Formula: see text] , ctHb, sO(2) and time (r(2)=0.77, p<0.000). Delayed cord clamping lactate was associated with immediate cord clamping lactate and time (r(2)=0.83, p<0.000). Delayed BE was associated with previous pH, lactate, glycemia, ctHb and time (r(2)=0.83, p<0.000).
CONCLUSIONS: Delayed cord clamping alters acid-base parameters and lactate values compared to immediate cord clamping. Those variations depend mainly on time, prior pH and lactate.
STUDY DESIGN: In a prospective observational study on 60 vaginally delivered healthy term newborns, we sampled umbilical cord blood immediately after delivery and at the time umbilical cord pulsation spontaneously ceased.
RESULTS: There were significant decreases in pH, oxygen saturation (sO(2)), glycemia, oxygen content (ctO(2)), bicarbonate (HCO(3)(-)) and base excess (BE). Lactate and [Formula: see text] increased. Delayed cord clamping pH correlated with immediate cord clamping pH, [Formula: see text] , ctHb, sO(2) and time (r(2)=0.77, p<0.000). Delayed cord clamping lactate was associated with immediate cord clamping lactate and time (r(2)=0.83, p<0.000). Delayed BE was associated with previous pH, lactate, glycemia, ctHb and time (r(2)=0.83, p<0.000).
CONCLUSIONS: Delayed cord clamping alters acid-base parameters and lactate values compared to immediate cord clamping. Those variations depend mainly on time, prior pH and lactate.