IJID regions · 2026
Okinawa's distinctive hepatitis B epidemiology reflected in 11-year seroprevalence trends among elderly long-term care residents in Japan.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kudeken Norifumi
Аннотация
OBJECTIVES: Okinawa has a distinctive hepatitis B virus (HBV) epidemiology characterized by historically high exposure and a predominance of genotype B. To examine how this regional background is reflected in the current elderly population, we analyzed 11-year serological trends in a long-term care facility in Okinawa.
METHODS: Annual hepatitis B surface antigen (HBsAg) and anti-hepatitis B surface antibody (anti-HBs) screening results for residents of a long-term care welfare facility in Okinawa from 2015 to 2025 were reviewed retrospectively. Seroprevalence was summarized annually and stratified by sex and ward. Facility records were also reviewed for HBV-related liver events and recorded causes of death during follow-up.
RESULTS: HBsAg prevalence remained low throughout the study period (0.8-3.6%), whereas anti-HBs prevalence remained relatively stable (32.1-47.8%). Women generally showed higher anti-HBs positivity. No significant ward-level difference in anti-HBs prevalence was detected (chi-square = 2.19, P = 0.34). No residents developed HBV-related hepatitis flares, cirrhosis, hepatocellular carcinoma, or documented HBV reactivation. Most recorded deaths were due to senility, with a small number due to aspiration pneumonia; no deaths were attributed to HBV-related liver disease.
CONCLUSION: Among elderly residents of this Okinawan long-term care facility, the combination of low HBsAg prevalence, stable anti-HBs positivity, and absence of HBV-related liver deaths is consistent with the region's long-recognized HBV background. These findings support region-sensitive HBV surveillance in long-term care settings.
METHODS: Annual hepatitis B surface antigen (HBsAg) and anti-hepatitis B surface antibody (anti-HBs) screening results for residents of a long-term care welfare facility in Okinawa from 2015 to 2025 were reviewed retrospectively. Seroprevalence was summarized annually and stratified by sex and ward. Facility records were also reviewed for HBV-related liver events and recorded causes of death during follow-up.
RESULTS: HBsAg prevalence remained low throughout the study period (0.8-3.6%), whereas anti-HBs prevalence remained relatively stable (32.1-47.8%). Women generally showed higher anti-HBs positivity. No significant ward-level difference in anti-HBs prevalence was detected (chi-square = 2.19, P = 0.34). No residents developed HBV-related hepatitis flares, cirrhosis, hepatocellular carcinoma, or documented HBV reactivation. Most recorded deaths were due to senility, with a small number due to aspiration pneumonia; no deaths were attributed to HBV-related liver disease.
CONCLUSION: Among elderly residents of this Okinawan long-term care facility, the combination of low HBsAg prevalence, stable anti-HBs positivity, and absence of HBV-related liver deaths is consistent with the region's long-recognized HBV background. These findings support region-sensitive HBV surveillance in long-term care settings.