ORL; journal for oto-rhino-laryngology and its related specialties · 2026
Patient Perspectives on a Hypothetical Olfactory Implant: A French Survey.
СтатьяНазвание и аннотация: Перевод в очереди
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Benkhatar Hakim, Bigot-Rablet Caroline, Maillard Jean-Michel, Martin Claire
Аннотация
INTRODUCTION: Smell loss severely impacts quality of life, and current treatment options remain limited. Emerging concepts such as olfactory implants, combining an external electronic nose and an intracranial neurostimulator, raise important questions regarding patient perceptions, expectations, and acceptability.
METHODS: The French patient organization <ext-link ext-link-type="uri" xlink:href="https://Anosmie.org" xmlns:xlink="http://www.w3.org/1999/xlink">Anosmie.org</ext-link> conducted an online survey among members experiencing smell loss. The study aimed to explore patient perceptions and expectations regarding a hypothetical olfactory implant. Questions addressed demographics, cause and duration of smell loss, perceived impact on quality of life, expectations and concerns related to such a device, its acceptability, and willingness to engage in future research.
RESULTS: A total of 226 patients completed the survey. The majority were women (71.7%), aged between 51 and 70 years (69%). Most participants reported anosmia (72.1%), lasting more than 4 years in 74.5% of cases. Causes were classified as idiopathic (39%), post-viral (32.3%), post-traumatic (25.2%), and toxic (3.5%). The perceived impact on quality of life and mental well-being was strong in 80.1% and 60.6% of cases, respectively. Openness toward an olfactory implant was high: 94.2% would consider it as a potential option, and 66.4% expressed willingness to engage in future research. Expected benefits were mainly related to food enjoyment and safety. Main concerns included fear of surgery, potential side effects, device visibility, and uncertain efficacy.
CONCLUSION: This survey highlights a substantial unmet need among patients with smell loss and provides insight into their perceptions and expectations regarding a potential neuroprosthetic solution. The findings suggest a high level of interest, conditioned by safety, efficacy, discretion, and clear information.
METHODS: The French patient organization <ext-link ext-link-type="uri" xlink:href="https://Anosmie.org" xmlns:xlink="http://www.w3.org/1999/xlink">Anosmie.org</ext-link> conducted an online survey among members experiencing smell loss. The study aimed to explore patient perceptions and expectations regarding a hypothetical olfactory implant. Questions addressed demographics, cause and duration of smell loss, perceived impact on quality of life, expectations and concerns related to such a device, its acceptability, and willingness to engage in future research.
RESULTS: A total of 226 patients completed the survey. The majority were women (71.7%), aged between 51 and 70 years (69%). Most participants reported anosmia (72.1%), lasting more than 4 years in 74.5% of cases. Causes were classified as idiopathic (39%), post-viral (32.3%), post-traumatic (25.2%), and toxic (3.5%). The perceived impact on quality of life and mental well-being was strong in 80.1% and 60.6% of cases, respectively. Openness toward an olfactory implant was high: 94.2% would consider it as a potential option, and 66.4% expressed willingness to engage in future research. Expected benefits were mainly related to food enjoyment and safety. Main concerns included fear of surgery, potential side effects, device visibility, and uncertain efficacy.
CONCLUSION: This survey highlights a substantial unmet need among patients with smell loss and provides insight into their perceptions and expectations regarding a potential neuroprosthetic solution. The findings suggest a high level of interest, conditioned by safety, efficacy, discretion, and clear information.