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DOI 10.1126/sciadv.adz5930

Медицинская библиотека · Science advances · 2025

Frog vocal sacs-inspired soft acoustic system with continuously tunable resonance for sound emission and stethoscopic sensing.

Liu Chuting, Dong Peiyan, Wang Jiantao, Deng Zhikang, Luo Jinan, Liu Chang, Wu Jingzhi, Tan Kaiyuan, Pan Jiajun, Han Rongkuan, Li Yuanfang, Chen Lvjie, Qu Xinyi, Ma Jianfeng, Zhou Qinghong, Yan Bojun, Ran Yu, Rong Dalun, Jiang Jianping, Li Bo, Ren Tian-Ling, Zhou Jianhua, Qiao Yancong

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Аннотация

To overcome limitations of flexible thermoacoustic devices in low-frequency emission and sensing, we present a resonance-adjustable graphene sound device (RAGSD) inspired by frog vocal sacs. Integrating laser-induced graphene (LIG) with a deformable cavity, RAGSD provides continuous tuning from 922.12 to 1762.90 hertz. A dynamic, continuously tunable electro-mechano-acoustical model explains the mechanism and predicts frequency with [Formula: see text] . In emission, a 25.34-decibel sound pressure level gain was observed at resonance, enabling controllable, frequency-selective voice amplification for personalized output. In sensing, the LIG piezoresistive readout delivers sensitive transduction, while resonance matching amplifies weak, high-frequency cardiac sounds. Wearable tests on healthy volunteers and patients recorded clear S1/S2 and pathological murmurs. Integrated with AuscNet-H, a deep learning algorithm designed for heart sound classification, the system achieved 99.375% accuracy across four clinical classes. Under inflation, no false negatives occurred, and misclassifications among similar diseases were fewer than with a commercial electronic stethoscope. These results demonstrate a practical path toward intelligent, wearable auscultation.

Для цитирования: Liu Chuting, Dong Peiyan, Wang Jiantao, Deng Zhikang, Luo Jinan, Liu Chang, Wu Jingzhi, Tan Kaiyuan, Pan Jiajun, Han Rongkuan, Li Yuanfang, Chen Lvjie, Qu Xinyi, Ma Jianfeng, Zhou Qinghong, Yan Bojun, Ran Yu, Rong Dalun, Jiang Jianping, Li Bo, Ren Tian-Ling, Zhou Jianhua, Qiao Yancong. Frog vocal sacs-inspired soft acoustic system with continuously tunable resonance for sound emission and stethoscopic sensing.. Science advances. 2025. DOI: 10.1126/sciadv.adz5930.

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