International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
Predictive value of peripheral blood α1-acid glycoprotein in medical abortion outcomes with mifepristone and relativity of concentration.
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Li Fuyao, Shou Yueyao, Zhu Ruru, Chen Xiue, Shi Beibei
Аннотация
OBJECTIVE: To illustrate the predictive value of peripheral blood α1-acid glycoprotein (AAG) in abortion outcomes with mifepristone and the relativity of concentration.
METHODS: A total of 134 patients who met the criteria were enrolled. The AAG and mifepristone concentrations were determined, and Student's t-test was used to assess significant differences in the levels of AAG between the complete and incomplete abortion groups.
RESULTS: The decrease in AAG concentration was associated with incomplete abortion, whereas the increase in AAG concentration was related to complete abortion (P < 0.01). In addition, the concentration of AAG was correlated with the concentration of mifepristone (r = 0.7375, P < 0.001).
CONCLUSION: Our preliminary results suggest that AAG may serve as a biomarker for the prediction of incomplete abortions.
METHODS: A total of 134 patients who met the criteria were enrolled. The AAG and mifepristone concentrations were determined, and Student's t-test was used to assess significant differences in the levels of AAG between the complete and incomplete abortion groups.
RESULTS: The decrease in AAG concentration was associated with incomplete abortion, whereas the increase in AAG concentration was related to complete abortion (P < 0.01). In addition, the concentration of AAG was correlated with the concentration of mifepristone (r = 0.7375, P < 0.001).
CONCLUSION: Our preliminary results suggest that AAG may serve as a biomarker for the prediction of incomplete abortions.