68Ga-DOTATATE and 68Ga-PSMA Uptake in Granulomatous Prostatitis.

68Ga-PSMA and 68Ga-DOTATATE PET/CT have shown promising performance in diagnosing prostate cancer and neuroendocrine tumors, but there are also pitfalls. We report a case of a 78-year-old man with prostate lesions showing intense uptake of 18FDG, 68Ga-PSMA, and 68Ga-DOTATATE simultaneously, with heterogeneous enhancement on contrast-enhanced CT and abnormal signal changes on PET/MRI. It was finally diagnosed as granulomatous prostatitis. This case suggests that granulomatous prostatitis has a high uptake of various imaging agents and is easily misdiagnosed as prostate cancer.