Triplet pregnancy after ovulation induction with an aromatase inhibitor.

OBJECTIVE

To describe the first reported case of a triplet pregnancy subsequent to the use of an aromatase inhibitor for ovulation induction.

DESIGN

Case report.

SETTING

Academic medical center.

PATIENT(S): A 32-year-old female with polycystic ovary syndrome and primary infertility.

INTERVENTION(S): Letrozole, 5 mg/day, on cycle days 2 to 6 for ovulation induction.

MAIN OUTCOME MEASURE(S): Clinical pregnancy.

RESULT(S): Viable triplet gestation.

CONCLUSION(S): Use of an aromatase inhibitor for ovulation induction does not eliminate the risk for higher order multiple pregnancy.