Knowledge, attitude and practice regarding metabolic complication management after solid organ transplantation among medical staff in China.

BACKGROUND

Metabolic complications are a major challenge after solid organ transplantation (SOT), impacting graft and patient survival. Understanding staff's knowledge, attitude, and practice (KAP) is crucial to optimize management.

METHODS

Utilizing data from a nationwide convenience sample (February-April 2025) of SOT clinicians and clinical pharmacists on the post-transplant metabolic complications management, this study analyzed 43-item KAP responses from 277 participants. Analyses included descriptive statistics, Spearman's correlation, and multinomial logistic regression to assess KAP levels and identify influencing factors.

RESULTS

Among 277 participants, the high-level rate for overall KAP was 67.5%, with high-level rates of 62.8, 88.1, and 56.3% for the knowledge, attitude, and practice dimensions, respectively. All three KAP dimensions were significantly positively correlated (r = 0.372-0.462, all p < 0.05). Multinomial logistic regression identified variables associated with high level of KAP. Significant positive factors included: female gender, a master's degree, and 10-19 years of work time for high-level knowledge; both 10-19 and ≥20 years of work time for high-level attitude; being a clinical physician for high-level practice; and age 36-44 years, a master's degree and vice senior or chief senior titles for a high-level overall KAP score. Age 45-60 years was negatively associated with high-level attitude.

CONCLUSION

Chinese SOT care providers demonstrate positive attitudes but suboptimal knowledge and practice in post-transplant metabolic complications management. Our study identifies self-reported educational needs and perceived practice gaps that may inform future training or quality-improvement initiatives.