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Computers in biology and medicine · 2025

SpectroNet-LSTM: An interpretable deep learning approach to cardiac anomaly detection through heartbeat sound analysis.

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Sharma Abhiram, Srivats R, P B Krishna, Mishra Utkarsh, R Krithiga, S Nachiyappan

Аннотация

Cardiac anomalies are severe and life-threatening, making early detection essential to reducing health risks and mortality. According to the European Society of Cardiology, over 13 million people suffer from heart valve diseases annually, often identified by heartbeat anomalies. Traditional diagnostic methods depend on specialized expertise and advanced equipment. This paper proposes SpectroNet-LSTM, an automated framework for detecting cardiac anomalies from a comprehensive dataset of heartbeat sound recordings. Mel-frequency cepstral coefficients (MFCCs) and spectrogram analysis are used to capture critical acoustic features. These features are then extracted and employed to train state-of-the-art deep learning models, including ResNet101, VGG16, and Inception V3. The core architecture is trained on the extracted features and optimized for improved performance. The model outperforms benchmarks on various evaluation metrics for detecting heart anomalies. To ensure system interpretability, the study integrates two Explainable AI (XAI) techniques, namely SHAP and LIME. These techniques enable clinicians and patients to visualize and understand the model's decision-making process. The novelty of SpectroNet-LSTM lies in its integrated use of advanced feature extraction, deep learning fusion and explainable AI to create a fully automated and interpretable cardiac anomaly detection system. This research underscores the potential of automation in transforming cardiovascular diagnostics, paving the way for accessible healthcare solutions and efficient patient outcomes worldwide.

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