A Cross-Sectional Study of Women's Cervical Cancer Knowledge and Acceptance of Human Papillomavirus Vaccination in Makeni, Sierra Leone.

Human papillomavirus (HPV) has become a major focus of improving health care in low- and middle-income countries. This study aims to contribute to existing literature by examining themes within Sierra Leonean women's knowledge and perception of cervical cancer and HPV as well as associations with different demographics. In this cross-sectional, door-to-door study, we conducted 189 interviews with women in rural and urban Sierra Leone using a questionnaire with four sections: demographics, women's perception and knowledge of cervical cancer, perception of the HPV vaccine, and demand-generating strategies. Among our findings were the overwhelming preference for Western medicine among participants and low awareness of cervical cancer, the HPV vaccine, and HPV. However, the vaccine is widely welcomed. Additionally, there is a statistically significant (p < .01) relationship between formal education attained and willingness to take the HPV vaccine. Policymakers and program directors may apply these results to the enhancement of immunization efforts.