Nihon Jibiinkoka Gakkai kaiho · 2002
[Clinicopathological study of salivary duct carcinoma].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Shimizu Akira, Yamane Masaaki, Ito Hiroyuki, Araki Susumu, Yoshida Tomoyuki, Suzuki Mamoru
Аннотация
Salivary duct carcinoma (SDC) was first described by Kleinsesser in 1968 and was classified as an independent entity by the 1991 Revised World Health Organization. It is a rare but highly malignant tumor. We reviewed pathology in 49 cases of salivary adenocarcinoma, and diagnosed 6 cases as SDC. All had a rapidly enlarged mass in the parotid gland. All were men, and 4 involved facial palsy and metastasis to cervical lymph nodes. Fine needle aspiration biopsy was conducted in 3 cases, but none was diagnosed as SDC. Two had chemotherapy, but showed no effect. All underwent surgery, but only 1 survived more than 4 years. Immunohistochemically, none showed s-100 protein. Four showed PCNA and p53 protein. Highly positive cells of PCNA and p53 were found around comedo necrosis.