International journal of surgery case reports · 2025
Bleb morphology following mitomycin-C sponge versus subconjunctival injection in deep sclerectomy for pediatric congenital glaucoma: A case report.
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Bamefleh Dania A, Halawani Mohammed A, Alosaimi Saad, Alonazi Raghad
Аннотация
INTRODUCTION AND IMPORTANCE: Congenital glaucoma poses a complex surgical challenge. Mitomycin-C (MMC) is frequently used to enhance surgical success, though the optimal method of application remains debated.
CASE PRESENTATION: We present a pediatric case of bilateral congenital glaucoma where two different MMC application methods were used: subconjunctival injection in one eye and sponge application in the other.
CLINICAL DISCUSSION: Despite initial IOP reduction in both eyes, the eye treated with sponge application showed progressive bleb thinning and compromise. The subconjunctival injection resulted in a stable, diffuse bleb with better long-term outcomes.
CONCLUSION: This case provides comparative intra-patient evidence favoring subconjunctival injection for improved bleb morphology and stability in pediatric glaucoma.
CASE PRESENTATION: We present a pediatric case of bilateral congenital glaucoma where two different MMC application methods were used: subconjunctival injection in one eye and sponge application in the other.
CLINICAL DISCUSSION: Despite initial IOP reduction in both eyes, the eye treated with sponge application showed progressive bleb thinning and compromise. The subconjunctival injection resulted in a stable, diffuse bleb with better long-term outcomes.
CONCLUSION: This case provides comparative intra-patient evidence favoring subconjunctival injection for improved bleb morphology and stability in pediatric glaucoma.