Hereditary painful callosities with associated features.

'Hereditary painful callosities' defines an autosomal dominant nummular palmoplantar keratoderma characterized by the development of painful keratotic lesions over pressure points. Two unrelated patients with hereditary painful callosities with other familial acral abnormalities are reported. To our knowledge subtotal congenital leukonychia and symmetrical bone duplication of great toes have not been previously described in association with this disorder.