[Infertility due to a pituitary gangliocytoma].

This tumor of hypophyseal origin is rare and its incidence is estimated from 2-5% of central nervous system neoplasms. It is characterized by enlargement of the sella turcica and by the presence of neuron with adenomatous tissue since it is derived form the neural crest. Clinical symptoms do not differ from pituitary adenomas. The diagnosis is made by histological analysis and prognosis is favorable after surgical excision. It is reported the case of a 27 year old female complaining of abnormal menses who was seen at our clinic due to primary infertility of 6 year duration and galactorrhea. An MRI disclosed a 7 mm lesion within the pituitary area. Prolactin was 167 ng/mL. The patient underwent transphenoidal surgery and the histological report was of gangliocytoma. Two months after surgery the patient resumed menses and 6 months later a MRI did not reveal residual tumor; prolactin levels decreased to 44.8 and 18 ng/mL. Afterwards, the patient became pregnant and had a normal delivery. To our knowledge this is the first report of infertility due to a pituitary gangliocytoma.