Lens coloboma and associated ocular malformations.

PURPOSE: Lens coloboma is a rare congenital disorder of crystalline lens characterized by notching of the equator of the lens. Coloboma can occur in isolation or with other ocular malformations. The authors reported 5 cases of lens coloboma associated with some ocular malformations.

METHODS

Case reports. The clinical features, imaging findings and associated ocular malformations were reported.

RESULTS

One case was not associated with ocular anomalies. One patient was involved with iris and choroid coloboma; another subject suffered from total cataract; and the fourth patient was affected by lens dislocation. The remaining case included aniridia. The pathogenic mechanisms and relationship of the ocular malformations have been discussed.

CONCLUSION

Lens coloboma can be associated with other ocular malformations, such as iris coloboma, choroid colobma, localized or total caratact.