Transcatheter Closure of Patent Ductus Arteriosus in Adults.

PURPOSE OF REVIEW: Data on transcatheter closure of patent ductus arteriosus (PDA) have been widely reported in pediatric but not adult patients. This paper serves as an overview of the currently available evidence and supplements it with additional data from our multi-centre registry.

RECENT FINDINGS: Transcatheter closure of PDA is safe and effective in adults, with up to 90-100% success rate. Our multi-centre registry shows similar findings with low risk of complications. Yet there are special anatomical, imaging and technical considerations compared to the pediatric population, and the common presence of pulmonary arterial hypertension complicates clinical decision-making. Transcatheter closure is less commonly performed in the adult population and is not as straightforward as commonly perceived. Given the paucity of studies reported in the current literature, further large-scale trials are needed to determine the optimal approach and long-term outcomes.