JACC. Case reports · 2025
First-in-Human Percutaneous Cor Triatriatum Sinistrum Balloon Membranoplasty to Facilitate Percutaneous Mitral Transcatheter Edge-to-Edge Repair.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Golzarian Hafez, Kleman Anna C, Knous Mallory, Macke Andrew H, Carder William C, Music Jennifer A, Carder Amy K, Imm Craig, Nelson Nicole A, Patel Sandeep M
Аннотация
BACKGROUND: Cor triatriatum sinistrum (CTS) is a rare congenital structural heart defect conventionally managed surgically early in life. However, at times it is discovered much later.
CASE SUMMARY: We present the first in-human case of a transcatheter CTS membranoplasty with mitral transcatheter edge-to-edge repair (mTEER) in an elderly patient with CTS. Ultimately, the patient experienced reduction in mitral regurgitation (MR), translating to significant symptomatic improvement.
DISCUSSION: Although surgical resection is the standard treatment for CTS, this approach may not be suitable for high-risk elderly individuals with multiple comorbidities. To address this, we employed a novel percutaneous technique, using multiple guidewires and balloons to facilitate controlled traversal and dilation of the atrial membrane, creating adequate space for mTEER.
TAKE-HOME MESSAGE: Percutaneous membranoplasty combined with mTEER may offer a feasible and potentially preferable alternative to surgery for elderly patients with CTS who are considered high-risk surgical candidates.
CASE SUMMARY: We present the first in-human case of a transcatheter CTS membranoplasty with mitral transcatheter edge-to-edge repair (mTEER) in an elderly patient with CTS. Ultimately, the patient experienced reduction in mitral regurgitation (MR), translating to significant symptomatic improvement.
DISCUSSION: Although surgical resection is the standard treatment for CTS, this approach may not be suitable for high-risk elderly individuals with multiple comorbidities. To address this, we employed a novel percutaneous technique, using multiple guidewires and balloons to facilitate controlled traversal and dilation of the atrial membrane, creating adequate space for mTEER.
TAKE-HOME MESSAGE: Percutaneous membranoplasty combined with mTEER may offer a feasible and potentially preferable alternative to surgery for elderly patients with CTS who are considered high-risk surgical candidates.