Annali italiani di chirurgia · 2014
Full restoration of spermatogenesis and male fertility after post-traumatic ectopic testis implant.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Allegretti Elisabetta, Luca Giovanni, Arato Iva, Falabella Giulia, Garolla Andrea, Maffia Romano, Ricci Giulia, Ghezzi Marco, Alfano Carmine, Foresta Carlo, Calafiore Riccardo
Аннотация
AIM: To restore testicular functional competence after traumatic avulsion of the scrotum, accompanied by penile decortication, by means of ad hoc surgery and post-surgical medical treatment.
MATERIALS AND METHODS: A 26 years old patient underwent a on the job perineal trauma that resulted in loss of one testis while the other one was rescued together with the deferential duct. The spared testis was buried in a subcutaneous thigh pocket after creating a tunnel from the inguinal area. Because of post-traumatic ensued hypogonadism, the patient was treated with corticosteroids, phosphodiesterase 5 inhibitors and anti-oxidizing agents.
RESULTS: Hypogonadism related clinical findings in terms of oligospermia, erectile dysfunction and alterations of the pituitary- testis axis, with low testosterone levels progressively improved along the post-traumatic months. Preservation of testis vascular supply associated with ad hoc medical therapy restored erectile dysfunction and spermatogenesis, and in the end at 6 months of the trauma the patients was able to regain fatherhood capability.
DISCUSSION: The obtained results demonstrate that an appropriate testis burying in the subcutaneous thigh region, upon traumatic scrotum avulsion, followed by an ad hoc medical therapy may rescue male fertility. This is unlikely to happen in the clinical routine and previous published reports negate restoration of the testis function, that completely vanishes within 1 year of the intervention.
CONCLUSION: Full restoration of testis and penile functions resulted in induction of spontaneous pregnancy in the patient's female partner may occur only if good reconstructive surgery is coupled with an efficient medical therapy.
MATERIALS AND METHODS: A 26 years old patient underwent a on the job perineal trauma that resulted in loss of one testis while the other one was rescued together with the deferential duct. The spared testis was buried in a subcutaneous thigh pocket after creating a tunnel from the inguinal area. Because of post-traumatic ensued hypogonadism, the patient was treated with corticosteroids, phosphodiesterase 5 inhibitors and anti-oxidizing agents.
RESULTS: Hypogonadism related clinical findings in terms of oligospermia, erectile dysfunction and alterations of the pituitary- testis axis, with low testosterone levels progressively improved along the post-traumatic months. Preservation of testis vascular supply associated with ad hoc medical therapy restored erectile dysfunction and spermatogenesis, and in the end at 6 months of the trauma the patients was able to regain fatherhood capability.
DISCUSSION: The obtained results demonstrate that an appropriate testis burying in the subcutaneous thigh region, upon traumatic scrotum avulsion, followed by an ad hoc medical therapy may rescue male fertility. This is unlikely to happen in the clinical routine and previous published reports negate restoration of the testis function, that completely vanishes within 1 year of the intervention.
CONCLUSION: Full restoration of testis and penile functions resulted in induction of spontaneous pregnancy in the patient's female partner may occur only if good reconstructive surgery is coupled with an efficient medical therapy.