Fertility and sterility · 2005
Inhibin A and activin A may be used to predict pregnancy outcome in women with recurrent miscarriage.
Клиническое исследованиеСравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Prakash Alka, Laird Susan, Tuckerman Elizabeth, Li Tin C, Ledger William L
Аннотация
OBJECTIVE: To look at the role of inhibin and activin in predicting pregnancy outcome in patients with history of recurrent miscarriage.
DESIGN: Observational clinical study.
SETTING: Recurrent miscarriage clinic of a tertiary care teaching hospital.
PATIENT(S): Patients with history of recurrent miscarriage.
INTERVENTION(S): Serial serum inhibin A and activin A concentrations were measured in weeks 5 though 8 of pregnancy.
MAIN OUTCOME MEASURE(S): Serum concentrations of inhibin A and activin A levels.
RESULT(S): Mean inhibin A concentration at 5 to 6 weeks for women who miscarried and those who had live births was 33 and 51 pg/mL, respectively; activin A at same gestation for the two groups was 534 and 643 pg/mL, respectively. After 2 weeks, mean inhibin A concentration for women who miscarried and those who had live births was 66 and 145 pg/mL, respectively, and activin A was 747 and 1,123 pg/mL, respectively.
CONCLUSION(S): It is possible that inhibin A and activin A may be used as markers to predict pregnancies that are likely to miscarry.
DESIGN: Observational clinical study.
SETTING: Recurrent miscarriage clinic of a tertiary care teaching hospital.
PATIENT(S): Patients with history of recurrent miscarriage.
INTERVENTION(S): Serial serum inhibin A and activin A concentrations were measured in weeks 5 though 8 of pregnancy.
MAIN OUTCOME MEASURE(S): Serum concentrations of inhibin A and activin A levels.
RESULT(S): Mean inhibin A concentration at 5 to 6 weeks for women who miscarried and those who had live births was 33 and 51 pg/mL, respectively; activin A at same gestation for the two groups was 534 and 643 pg/mL, respectively. After 2 weeks, mean inhibin A concentration for women who miscarried and those who had live births was 66 and 145 pg/mL, respectively, and activin A was 747 and 1,123 pg/mL, respectively.
CONCLUSION(S): It is possible that inhibin A and activin A may be used as markers to predict pregnancies that are likely to miscarry.