Bempedoic acid for prevention of atherosclerotic cardiovascular disease: from trials to clinical practice.

AIMS: This viewpoint discusses the current role of bempedoic acid in clinical practice.

DATA SYNTHESIS: Randomized clinical trials have shown bempedoic acid efficacy in both reducing LDL-C levels and major cardiovascular adverse events. This evidence has led to the inclusion of bempedoic acid among the lipid-lowering therapies with demonstrated clinical efficacy and recommended by the last update of European Society of Cardiology guidelines on dyslipidaemia management to prevent cardiovascular disease.

CONCLUSIONS

Bempedoic acid is an important therapeutic option that overcomes some limitations of statins and allows to further reduce the global burden of atherosclerotic cardiovascular disease.