Artificial Intelligence Applications in Pediatric Craniofacial Surgery.

Artificial intelligence is rapidly transforming pediatric craniofacial surgery by enhancing diagnostic accuracy, improving surgical precision, and optimizing postoperative care. Machine learning and deep learning models are increasingly used to analyze complex craniofacial imaging, enabling early detection of congenital anomalies such as craniosynostosis, and cleft lip and palate. AI-driven algorithms assist in preoperative planning by identifying anatomical abnormalities, predicting surgical outcomes, and guiding personalized treatment strategies. In cleft lip and palate care, AI enhances prenatal detection, severity classification, and the design of custom therapeutic devices, while also refining speech evaluation. For craniosynostosis, AI supports automated morphology classification, severity scoring, and the assessment of surgical indications, thereby promoting diagnostic consistency and predictive outcome modeling. In orthognathic surgery, AI-driven analyses, including skeletal maturity evaluation and cephalometric assessment, inform optimal timing and diagnosis. Furthermore, in cases of craniofacial microsomia and microtia, AI improves phenotypic classification and surgical planning through precise intraoperative navigation. These advancements underscore AI's transformative role in diagnostic accuracy, and clinical decision-making, highlighting its potential to significantly enhance evidence-based pediatric craniofacial care.