Frontiers in pediatrics · 2026
Multidisciplinary management promoting wound healing in a patient with Proteus syndrome: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tan Yue, Zhang Xu, Wang Hai-Bin, Wang Li, Qiu Wen-Shuang
Аннотация
INTRODUCTION: Proteus syndrome is caused by AKT1 gene mutations. It manifests during childhood and results in asymmetric overgrowth of skin, bone, central nervous system, and adipose tissues and has a poor survival rate. Currently, there are no targeted drug treatments for this condition. Due to its rarity, the nonspecific symptoms and complications of Proteus syndrome often go unrecognized and, thus, untreated by clinicians.
CASE DESCRIPTION: This case report documents the diagnosis and treatment of a 14-year-old patient with Proteus syndrome who developed severe soft tissue infection secondary to lower limb deformity. A clinical pharmacist implemented individualized anti-infective interventions based on etiology, liver function, and body weight, significantly optimizing the treatment course and promoting wound healing.
DISCUSSION: Through this report, we aim to enhance awareness of the diverse clinical presentations of Proteus syndrome and emphasize the need for a coordinated healthcare approach to effectively manage its associated complications.
CASE DESCRIPTION: This case report documents the diagnosis and treatment of a 14-year-old patient with Proteus syndrome who developed severe soft tissue infection secondary to lower limb deformity. A clinical pharmacist implemented individualized anti-infective interventions based on etiology, liver function, and body weight, significantly optimizing the treatment course and promoting wound healing.
DISCUSSION: Through this report, we aim to enhance awareness of the diverse clinical presentations of Proteus syndrome and emphasize the need for a coordinated healthcare approach to effectively manage its associated complications.