Inter-Limb Asymmetry and Its Limited Role in Physical Performance and Match Demands in Football Players with Spastic Hemiparesis-An Exploratory Team Study.

Background: Inter-limb asymmetry has been widely studied as a potential determinant of physical performance in able-bodied athletes; however, its functional relevance in athletes with neurological impairments such as spastic hemiparesis remains unclear. This study aimed to examine the associations between lower-limb isometric strength, inter-limb asymmetry, physical performance, and match external-load variables in elite CP football players. Methods: Eleven male football players with spastic hemiparesis from the Spanish national team competing at the 2024 IFCPF World Cup participated in this observational cross-sectional study. Maximal isometric strength of the plantar flexors, adductors, and hamstrings was assessed using a belt-stabilised dynamometer. Inter-limb asymmetry was calculated as a percentage difference between affected and non-affected limbs. Physical performance was evaluated using sprint, change-of-direction, dribbling, and intermittent endurance tests. Match external-load variables were collected during official competition using inertial measurement units. Associations were analysed using Spearman's rank correlations, and between-group comparisons were conducted using a median split based on asymmetry magnitude. Results: Inter-limb asymmetry did not significantly differentiate physical performance outcomes across any field-based tests (p > 0.05). Associations between isometric strength or asymmetry and field-based performance were limited and did not remain statistically significant after false discovery rate correction. In contrast, plantar flexor asymmetry showed significant negative associations with mechanical work (ρ = -0.84; q = 0.010) and metabolic power (ρ = -0.83; q = 0.010), which remained robust after multiple-comparison control. Conclusions: Inter-limb strength asymmetry did not appear to be a primary determinant of field-based physical performance in CP football players with spastic hemiparesis. Most associations between strength, asymmetry, and performance should be considered exploratory. However, plantar flexor asymmetry showed a consistent association with selected mechanical and metabolic match-load variables, suggesting that neuromuscular asymmetry may influence specific aspects of match demands. Given the exploratory team-study design and limited sample size, these findings should be interpreted cautiously and require confirmation in larger cohorts.