A New Situation-Specific Theoretical Framework to Guide Ectopic Pregnancy Research in Nursing.

Ectopic pregnancy (EP) is a serious and increasing health concern that remains poorly understood despite identified risk factors. This article introduces the N-GEM Theoretical Framework, a novel approach that integrates genomic, epigenomic, environmental, and microbiome factors to address the complex and multifactorial etiology of EP. By offering a comprehensive and dynamic model, the N-GEM framework supports the development of personalized prevention strategies and can enhance early detection methods. This situation-specific theoretical framework not only positions nursing at the forefront of EP research but also fosters interdisciplinary collaboration that can drive significant advancements in clinical practice and ultimately reduce EP-related morbidity and mortality.