[Two patients with CC9 intoxication: unexpected symptoms of a novel synthetic cannabinoid].

BACKGROUND

Hexahydrocannabinol-C9 (CC9) is a novel synthetic cannabinoid with largely unknown toxicity and clinical effects.

CASE DESCRIPTION: We report two patients with CC9 intoxication presenting with atypical and prolonged symptoms, including profound somnolence, bradycardia, neuropsychiatric disturbances, and impaired mobility. Both patients experienced a protracted course lasting up to 90 hours.

MANAGEMENT: Treatment was primarily focused on symptom control in a low-stimulus environment. Close monitoring of respiratory function was essential in cases of profound sedation, while benzodiazepines were administered when severe agitation occurred. Activated charcoal combined with a laxative was used in one case and may have contributed to recovery by reducing intestinal reabsorption.

CONCLUSION

Clinicians should be alert to the atypical and prolonged course of intoxications caused by new synthetic cannabinoids such as CC9. Early recognition, multidisciplinary consultation, and supportive treatment in a low-stimulus environment are essential.