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DOI 10.1093/jalm/jfae076

Медицинская библиотека · The journal of applied laboratory medicine · 2024

Impact of COVID-19 on Drug Positivity Rates in the Emergency Departments in Boston and Surrounding Areas.

Tolan Nicole V, Kang Phillip, Chai Peter R, Erickson Timothy B, Hayes Bryan D, Uljon Sacha N, Demetriou Christiana A, Melanson Stacy E F

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Аннотация

BACKGROUND

The COVID-19 pandemic reportedly had a significant impact on drug and alcohol use. In this article, we determine positivity rates for urine drugs of abuse and blood alcohol in 5 emergency departments (ED) in the greater Boston metropolitan area over a 4-year period (pre-, during, and post-COVID-19 pandemic).

METHODS

Positivity rates for the urine drug screening (UDS) panel and blood alcohol concentration (>80 mg/dL; over the legal limit in MA) were calculated in patients presenting to one of the 5 ED (2 academic hospitals in Boston, MA and 3 community hospitals outside Boston, MA) during each of the 4 different time periods: pre-COVID (January 1, 2019 to December 31, 2019), stay-at-home (March 24, 2020 to May 18, 2020), during COVID (May 19, 2020 to March 28, 2021), and post-COVID (May 12, 2023 to August 31, 2023). Trend analysis was performed. Additionally, positivity rates during and post-COVID were compared to pre-COVID to determine any significant changes in drug positivity.

RESULTS

Stimulant (amphetamines and cocaine), cannabinoid, and methadone positivity increased during the pandemic and cocaine, cannabinoid, and methadone positivity remains elevated. By contrast, benzodiazepine and opioid (opiates, fentanyl, oxycodone) positivity decreased and remains lower post-COVID compared to pre-COVID. Patients in the ED with blood alcohol over the legal limit decreased both during and post-COVID.

CONCLUSION

Our study showed that the COVID-19 pandemic significantly affected drug and alcohol positivity rates in patients presenting to the ED in greater Boston area. We encourage other institutions to perform similar analyses to help determine local drug use patterns and appropriate composition of UDS panels.

Для цитирования: Tolan Nicole V, Kang Phillip, Chai Peter R, Erickson Timothy B, Hayes Bryan D, Uljon Sacha N, Demetriou Christiana A, Melanson Stacy E F. Impact of COVID-19 on Drug Positivity Rates in the Emergency Departments in Boston and Surrounding Areas.. The journal of applied laboratory medicine. 2024. DOI: 10.1093/jalm/jfae076.

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