[Effects of vitamin D on non-classical target organs and survival].

Impaired activation of vitamin D in renal failure results in bone and mineral abnormalities, and causes renal osteodystrophy or chronic kidney disease mineral and bone disorder (CKD-MBD). Recent studies suggest that deficiency of active vitamin D is also involved in abnormalities in blood pressure, cardiac hypertrophy, atherosclerosis, glucose intolerance and immune dysfunction that are known as complications of uremia. This article reviews these extra-renal actions of vitamin D and its impact on survival of dialysis patients.