Bicuspid Aortic Valves (BAV) Registry (RE-BAV): Clinical and echocardiographic characteristics of patients with BAV according to novel classification of bicuspid aortic valves.
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Płońska-Gościniak Edyta, Tomkiewicz-Pająk Lidia, Komar Monika, Kukulski Tomasz, Kosmala Wojciech, Kasprzak Jarosław D, Mizia-Stec Katarzyna, Hryniewiecki Tomasz, Kustrzycka-Kratochwil Dorota, Niklewski Tomasz, Daniłowicz-Szymanowicz Ludmiła, Sorysz Danuta, Braksator Wojciech, Pilchowska-Paszkiet Ewa, Gackowski Andrzej, Gąsior Zbigniew, Zych Andrzej, Kowalik Ilona, Gościniak Piotr, Scisło Piotr, Knapp Małgorzata, Garbowska Marta, Wojtkowska Agnieszka, Dankowski Rafał, Biernat Jolanta, Lipczyńska Magda, Minczykowski Andrzej, Dąbrowska-Kugacka Alicja
Аннотация
AIMS: To present BAV types and valvulo-aortopathy in the Polish population using the latest 2021 classification.
METHODS: RE-BAV is a registry of adult ambulatory and hospitalized patients with BAV evaluated in echocardiographic laboratories at 23 tertiary centers in Poland (2021-2023).
RESULTS: The study included 814 patients - 72.7% male, average age - mean (SD) 50 (17.4). Common symptoms included dyspnea (54.1%) and chest pain (17.5%). Hypertension (54%) was the most frequent comorbidity. Left ventricular ejection fraction was normal (median 60%, interquartile range: 55-65), but global longitudinal strain was mildly reduced - mean (SD) - 16.8% (3.7). Moderate/severe aortic stenosis was found in 34.2% and regurgitation in 44.1% (P < 0.001). The most common phenotype was typical valvulo-aortopathy (69.9%), followed by uncomplicated BAV (19.3%) and complex valvulo-aortopathy (10.8%). Among 640 patients with specified subtypes, fusion was the most frequent BAV type (79.4%), followed by 2-sinus (15.8%) and partial-fusion (4.8%) (P < 0.001 for all comparisons). Patients with the 2-sinus type were the youngest and had the least comorbidities, contrary to the partial-fusion group. Right-left cusp fusion was the most common subtype (80.4% of fusion BAV). Within the 2-sinus type the latero-lateral and antero-posterior phenotypes had similar prevalence. Aortic dilatation occurred in 63.6%, with extended aortic dilatation being most prevalent (26.3%).
CONCLUSIONS: The RE-BAV registry provides updated insights into BAV phenotypes and aortopathy in the Polish population, reflecting the latest classification advancements. .