Methamphetamine and Ecstasy-Induced Acute Reversible Cerebellar Neurotoxicity in a 3-Year-Old Child: A Case Report.

The prevalence of substance use disorders is increasing among children and adolescents. We present a case of a 3-year-old girl who was admitted to our hospital with complaints of acute onset difficulty walking and speaking. Neurological examination revealed dysarthria, truncal ataxia, hypotonia, and hyporeflexia. Brain magnetic resonance imaging, cerebrospinal fluid analysis, and routine blood and urine analyses were normal. Urine drug testing revealed positive results for ecstasy and methamphetamine. The patient's symptoms improved during hospitalization. To our knowledge, this is the youngest reported case of methamphetamine and ecstasy-induced acute reversible cerebellar neurotoxicity. It is essential to carefully monitor acute reversible neurological symptoms related to methamphetamine and ecstasy.