Clinics (Sao Paulo, Brazil) · 2025
Motivations for uterus transplantation in women with absolute uterine factor infertility: A systematic review of the literature.
СтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
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Leis Luciana, Tustumi Francisco, Soares-Jr José Maria, Baracat Edmund Chada, Carneiro-D'Albuquerque Luiz Augusto, Ejzenberg Dani, Andraus Wellington
Аннотация
INTRODUCTION: Uterine transplantation is indicated for women with absolute uterine factor infertility, which is usually associated with congenital causes (the most common being Mayer-Rokitansky-Kuster-Hauser syndrome) or acquired via hysterectomy. For these women, uterus transplantation is the only possibility for them to be able to conceive and have a biological child. The aim of this study was to understand the motivations that lead women with absolute uterine factor infertility to wish to undergo a uterus transplant.
METHODS: A systematic literature review was performed in the following databases: Medline (PubMed), Embase, Cochrane (CENTRAL), Scopus, Web of Science, and LILACS.
RESULTS: 439 articles were identified, and nine studies were finally selected. Uterine transplantation was the preferred choice over adoption and surrogacy in most studies (ranging from 45 % to 97.5 %). The main motivations for this type of transplant include the desire to conceive a pregnancy, the desire to have a genetic child, the desire to have control over pregnancy, the physiological repair of the body, the restoration of femininity, and the desire to contribute to science.
CONCLUSION: The motivations for uterus transplantation go far beyond the desire to get pregnant and include personal and unique motivations.
METHODS: A systematic literature review was performed in the following databases: Medline (PubMed), Embase, Cochrane (CENTRAL), Scopus, Web of Science, and LILACS.
RESULTS: 439 articles were identified, and nine studies were finally selected. Uterine transplantation was the preferred choice over adoption and surrogacy in most studies (ranging from 45 % to 97.5 %). The main motivations for this type of transplant include the desire to conceive a pregnancy, the desire to have a genetic child, the desire to have control over pregnancy, the physiological repair of the body, the restoration of femininity, and the desire to contribute to science.
CONCLUSION: The motivations for uterus transplantation go far beyond the desire to get pregnant and include personal and unique motivations.