World journal of clinical cases · 2026
Left ventricular mass in newborn with perinatal asphxia: Assessment of allometric relations and impact of birth weight.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chinawa Josephat M, Ani Okechukwu S, Odetunde Odutola I
Аннотация
BACKGROUND: Utero-placental insufficiency seen in perinatal asphyxia may adversely affect left ventricular (LV) geometry.
AIM: To document the LV mass values in perinatal asphyxia and to elicit associated factors.
METHODS: This was a cross-sectional study conducted in a tertiary health facility among newborns with perinatal asphyxia. Echocardiography was used to compare the LV mass of 84 new-borns with perinatal asphyxia with the LV mass of 48 new-borns without perinatal asphyxia matched for age. The data was analysed using SPSS version 25 (IBM, United States).
RESULTS: The mean LV mass (7.9 ± 2.3 g) of perinatal asphyxia is lower than control (10.1 ± 0.7 g) P = 0.001. New-borns with severe perinatal asphyxia had the lowest mean LV mass (7.1 ± 1.5), while the moderate group had the highest (8.8 ± 2.5), with the Analysis of Variance (ANOVA) result of F = 1.26 and P = 0.289. The mean LV mass was highest on day 1 (8.1 ± 2.5) and slightly lower on days 2 and 3 (both 7.7 ± 1.9 and 7.7 ± 2.0, respectively). Though ANOVA result (F = 2.47, P = 0.7282) indicates no significant relationship between the age of the newborn and LV mass, a weak positive correlation was observed between LV mass and gestational age which is statistically significant (r = 0.269 P = 0.028). A moderate positive correlation between the LV mass and birth weight of newborn was observed. This is statistically significant (r = 0.610, P = 0.001). There was weak negative correlation (r = -0.10, P = 0.752), between LV mass and age of the newborn without perinatal asphyxia but a moderate positive correlation (r = 0.69, P = 0.015) was observed, between LV mass and weight in non-asphyxiated newborn.
CONCLUSION: This study showed that the LV mass in perinatal asphyxia was significantly lower than those without asphyxia. There was a direct correlation between LV mass and birth weight of neonates with perinatal asphyxia. Early detection of the cardiac disease, appropriate management and sustained reduction of birth asphyxia, and improved intra-partum quality of care are key.
AIM: To document the LV mass values in perinatal asphyxia and to elicit associated factors.
METHODS: This was a cross-sectional study conducted in a tertiary health facility among newborns with perinatal asphyxia. Echocardiography was used to compare the LV mass of 84 new-borns with perinatal asphyxia with the LV mass of 48 new-borns without perinatal asphyxia matched for age. The data was analysed using SPSS version 25 (IBM, United States).
RESULTS: The mean LV mass (7.9 ± 2.3 g) of perinatal asphyxia is lower than control (10.1 ± 0.7 g) P = 0.001. New-borns with severe perinatal asphyxia had the lowest mean LV mass (7.1 ± 1.5), while the moderate group had the highest (8.8 ± 2.5), with the Analysis of Variance (ANOVA) result of F = 1.26 and P = 0.289. The mean LV mass was highest on day 1 (8.1 ± 2.5) and slightly lower on days 2 and 3 (both 7.7 ± 1.9 and 7.7 ± 2.0, respectively). Though ANOVA result (F = 2.47, P = 0.7282) indicates no significant relationship between the age of the newborn and LV mass, a weak positive correlation was observed between LV mass and gestational age which is statistically significant (r = 0.269 P = 0.028). A moderate positive correlation between the LV mass and birth weight of newborn was observed. This is statistically significant (r = 0.610, P = 0.001). There was weak negative correlation (r = -0.10, P = 0.752), between LV mass and age of the newborn without perinatal asphyxia but a moderate positive correlation (r = 0.69, P = 0.015) was observed, between LV mass and weight in non-asphyxiated newborn.
CONCLUSION: This study showed that the LV mass in perinatal asphyxia was significantly lower than those without asphyxia. There was a direct correlation between LV mass and birth weight of neonates with perinatal asphyxia. Early detection of the cardiac disease, appropriate management and sustained reduction of birth asphyxia, and improved intra-partum quality of care are key.