Surgical outcomes after robot-assisted versus laparoscopic pancreatoduodenectomy: multicentre propensity-matched comparison from the Italian Group of Minimally Invasive Pancreatic Surgery.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Quero Giuseppe, Menghi Roberta, Napoli Niccolò, Ripolli Allegra, Ferrari Giovanni, Mazzola Michele, Bannone Elisa, Butturini Giovanni, Viola Massimo Giuseppe, Garatti Marco, Tebala Giovanni, Di Benedetto Fabrizio, Moraldi Luca, Molino Carlo, Alfieri Sergio, Bracale Umberto, Troisi Roberto, Dalla Valle Raffaele, Vivarelli Marco, Jovine Elio, Memeo Riccardo, Garulli Gianluca, Ottaviani Luca, Berti Stefano, Coratti Andrea, Ercolani Giorgio, Salvia Roberto, Morelli Luca, Casadei Riccardo, Coppola Roberto, Brolese Alberto, Tondolo Vicenzo, Zerbi Alessandro, Boggi Ugo, IGOMIPS Registry Study Group
Аннотация
METHODS: This retrospective multicentre study included patients who underwent LPD or RPD at participating Italian centres within the Italian Group of Minimally Invasive Pancreas Surgery registry between October 2019 and December 2024. Propensity score matching was performed in a 1 : 1 ratio based on age, body mass index, American Society of Anaesthesiologists score, tumour type (pancreatic ductal adenocarcinoma versus other histologies), receipt of neoadjuvant chemotherapy, and requirement for vascular and/or organ resection. Primary outcomes were estimated blood loss and operative time. Secondary outcomes included conversion rate, postoperative morbidity, pancreas-related complications, reoperation, length of hospital stay, histopathological features, and deaths.
RESULTS: Among 774 minimally invasive PDs, 163 (21.1%) were LPD and 611 (78.9%) were RPD. After propensity score matching , 161 LPDs were compared with 161 RPDs. RPD was associated with a longer operative time (median 506 (interquartile range (i.q.r.) 427.5-600) versus 500 (411.5-551) minutes; P = 0.030) but lower estimated blood loss (median 200 (i.q.r. 100-337.5) ml versus 250 (150-500) ml; P < 0.001). On multivariable analysis, surgical approach was not an independent predictor of operative time, whereas RPD was independently associated with lower estimated blood loss (β -0.372, 95% confidence interval -0.641 to -0.102; P = 0.007). Conversion to open surgery was significantly more frequent after LPD (24 of 161; 14.9%) than RPD (11 of 161; 6.8%) (P = 0.023). Postoperative outcomes-including major morbidity, pancreas-specific complications, reoperation, length of hospital stay, and in-hospital or 90-day deaths-were comparable between groups. Histopathological findings were also similar.
CONCLUSION: RPD was associated with lower estimated blood loss and a reduced conversion rate compared with LPD. However, these differences were modest in absolute terms and did not translate into clinically meaningful differences in postoperative outcomes, which remained comparable between the two approaches.