Detection and Identification of Alkenes and Alkynes Using a 19F-Labeled NMR Probe.

We report a trifluoromethyl-labeled copper(I) complex probe that, in combination with 19F NMR spectroscopy, enables rapid and specific detection of alkene and alkyne compounds. The probe operates based on dynamic coordination interactions between the Cu(I) center and unsaturated hydrocarbons, converting recognition events into distinct 19F NMR signal changes, thereby allowing "separation-free" analysis without requiring complex sample pretreatment. Experimental results demonstrate that the probe can effectively discriminate between terminal and disubstituted alkynes, distinguish structurally similar compounds and regioisomers, and simultaneously identify multiple alkene and alkyne components in mixed samples, showing good anti-interference capability and potential for multiplexed analysis. This method offers a simple, sensitive, and reliable new strategy for the rapid identification and structural analysis of unsaturated compounds in complex matrices.