An Alarming Sign: Acute Limb Ischemia in Patients With COVID-19.

Acute limb ischemia (ALI) can occur as a late complication in patients recovering from COVID-19. Although typically seen during the acute phase, ALI may present weeks to months later, making diagnosis more challenging. Symptoms, including acute limb pain, pallor, coldness, and absent pulses, can be misattributed to other post-viral issues. COVID-19 induces a prothrombotic state that persists after recovery, with increased D-dimer, fibrinogen, and endothelial dysfunction contributing to thrombus formation. Early diagnosis through clinical assessment and imaging is crucial to prevent irreversible limb damage. Treatment involves anticoagulation, revascularization, and supportive care, tailored to the patient's condition. Vigilance for late-onset ALI in post-COVID-19 patients is essential to improve outcomes and prevent limb loss.