Parthenolide reduces gene transcription of prosurvival mediators in U937 cells.

INTRODUCTION

Oral and maxillofacial (OMF) injuries encompass all forms of trauma to the tissues of the oro-facial complex, the face, jaws and mouth. In rural areas, where healthcare access is often limited, OMF injuries pose unique challenges. These challenges are compounded by environmental factors, occupational hazards and socioeconomic disparities, making rural populations particularly vulnerable to such injuries. This study explores the epidemiology and geographical variation of OMF injuries in Queensland, Australia.

METHODS

Data for injury from several Queensland hospital emergency departments were obtained from state register Queensland Injury Surveillance Unit for the years 2015-2021. Data parameters included patient demographics, mechanism, intent and location of injury.

RESULTS

The data (n=9095) revealed that OMF injuries are more prevalent in rural areas and increasing in incidence. Those in inner and outer regional areas sustained injuries 1.8-2.2 times more than the metropolitan population and the incidence was 8.7-11.7 times higher in remote and very remote locations (p<0.05). Approximately 70% of injuries occurred among males in all populations, with peak age of injuries noted as 15-24 years. Assault-related injuries were the predominant cause of injury, notably more common in regional (35.6%) and remote (45.7%) areas compared to metropolitan regions (19.8%) (p<0.05).

CONCLUSION

The high proportion of OMF injuries experienced in rural areas signifies a considerable health concern. This may be attributable to engagement in risk-taking behaviours, contributing as aetiology or exacerbators. These findings underscore the need for targeted interventions aimed at addressing the mental health and risky behaviour patterns in rural communities. Further research should consider wider aetiological and exacerbating factors including social determinants of health, ethnicity and cultural factors that underlie interpersonal violence in these communities.