The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
Unusual Association of Orofacial Cleft and Finger-Like Skin Appendages With or Without Constriction Rings: A Disorganization-Like Phenotype?
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Serigatto Henrique Regonaschi, Vendramini-Pittoli Siulan, Moura Priscila Padilha, Virmond Luiza, Segarra Vinicius Contrucci Dantas, da Cunha José Humberto, Rosenberg Carla, Zechi-Ceide Roseli Maria, Kokitsu-Nakata Nancy Mizue
Аннотация
The mouse disorganization (Ds) was described in mutant mice with multiple congenital anomalies arising from the 3 germinative layers. The human homologue of Ds was proposed in a case presenting multiple congenital anomalies associated with the unique feature of a finger-like skin appendage. Since then, several cases have been reported suggesting the occurrence of a disorganization-like (Ds-like) phenotype in humans. Here, we report a case series of 7 patients presenting with the association of orofacial clefts and finger-like skin appendages. These cases, despite the similarities with Ds and amniotic band sequence, may represent a distinct condition within the spectrum of Ds-like, as other cases previously reported in the literature.