A second case of microcephaly, microphthalmia, ectrodactyly (split-foot) and prognathism (MMEP).

In 1993, Viljoen and Smart described a woman with ectrodactyly of the feet, midline facial cleft, microphthalmia, and mental retardation in association with a de novo chromosome 6;13 translocation. We present a man with similar features who had a normal karyotype.