[Primary Pharmacodynamic Study on Chuanping Dropping Pills].

OBJECTIVE

To study the antitussive, antiasthmatic, and expectorant effects of Chuanoing dropping pills.

METHODS

Histamine-acetylcholine induced asthma, ovalbumin sensitization, pulmonary overflow, spiral strip trachea of guinea pig, lung strip of guinea pig, ammonia water or citric acid induced cough of mice, and phenol red expectoration of mice were carried out.

RESULTS

Chuanping dripping pills significantly prolonged the incubation induced by histamine-acetylcholine, reduced the reaction stage of ovalbumin sensitization of guinea pig with asthma, inhibited the increase of pulmonary overflow on histamine induced asthma, reduced the contraction of smooth muscle and lung strip by histamine induced asthma on guinea pig, reduced cough times on ammonia or citrate acid caused mice, and increased the output on mice tracheal phenol red.

CONCLUSIONS

Chuanping dropping pills have significant effect on antitussive, antiasthmatic and expectorant actions.