Head & neck · 2008
Anaplastic lymphoma of the cervical esophagus presenting as a tracheoesophageal fistula.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Joshi Anil, Fields Paul, Simo Ricard
Аннотация
BACKGROUND: Anaplastic kinase-1 positive lymphoma (ALK-1) is a very rare but distinct pathologic entity. ALK-1 lymphoma tends to affect the bone marrow, skin, lungs, soft tissue, but very rarely the gastrointestinal tract.
METHODS: We report a case of ALK-1 positive lymphoma presenting as a tracheoesophageal fistula. The clinical presentation, histopathology, and management outcome are all discussed.
CONCLUSION: ALK-1 positive lymphoma of the upper aerodigestive involvement is extremely rare. An unusual presentation such as pharyngeal pouch with vocal cord palsy should suggest pathology. Histopathologic analysis can be difficult and immunohistochemical studies will aid are of paramount importance in the diagnosis and help in subsequent management and also act as prognostic indicators.
METHODS: We report a case of ALK-1 positive lymphoma presenting as a tracheoesophageal fistula. The clinical presentation, histopathology, and management outcome are all discussed.
CONCLUSION: ALK-1 positive lymphoma of the upper aerodigestive involvement is extremely rare. An unusual presentation such as pharyngeal pouch with vocal cord palsy should suggest pathology. Histopathologic analysis can be difficult and immunohistochemical studies will aid are of paramount importance in the diagnosis and help in subsequent management and also act as prognostic indicators.
Предметные рубрики MeSH
Antineoplastic Combined Chemotherapy ProtocolsBiopsy, NeedleCervical VertebraeCombined Modality TherapyDiagnosis, DifferentialEsophageal NeoplasmsEsophagoscopyFollow-Up StudiesHumansImmunohistochemistryLymphoma, Large-Cell, AnaplasticMaleMiddle AgedNeoplasm StagingPhotomicrographyRisk AssessmentSalvage TherapyStem Cell TransplantationTomography, X-Ray ComputedTracheoesophageal FistulaTransplantation, AutologousTreatment Outcome