Risk estimation of intraamniotic infection development after serial amniocentesis.

Microbial invasion and growth in amniotic fluid play an important role in infectious perinatal morbidity and mortality. In order to determine the influence of amniocentesis (ACT) on intra-amniotic infection development, we performed a study of 239 complete microbiological examinations of amniotic fluid specimens obtained by serial interventions. In 1 case (0.42%), during the second procedure, Staphylococcus epidermidis was discovered. Neither spontaneous abortion nor preterm labor were provoked by the procedure. We can conclude that ACT has been confirmed as a safe and successful intrauterine intervention if it is made in a proper manner.