Needleless connectors: A small device with big consequences.

Vascular access devices (VADs), including both peripheral intravenous (IV) catheters and central VADs, are used across the continuum of health care to administer IV fluids, medications, and diagnostics. Needleless connectors (NCs) are a critical component of the infusion system providing needle-free access to VADs yet many nurses are unaware of their significant impact on VAD-related complications, including infection, thrombotic occlusion, and catheter malfunction. This article provides a review of the critical role of the nurse in identifying risks and applying best practices in NC care, including disinfection, clamping, flushing, and timely replacement. Proper technique and adherence to evidence-informed protocols are vital to maintaining VAD performance and reducing adverse events.