Management of Multidrug-Resistant Acinetobacter Infection Following Open Reduction and Internal Fixation of a Right Acetabular Fracture: A Case Report.

Postoperative infections with multidrug-resistant (MDR) Acinetobacter baumannii present significant challenges in orthopedic surgery. This case report highlights the management and successful treatment of an MDR Acinetobacter infection following open reduction and internal fixation (ORIF) of a right acetabulum fracture. A 51-year-old male presented with a comminuted right acetabular fracture following a motor vehicle accident. Initial ORIF was complicated by intraoperative blood loss, necessitating early termination of the procedure. The patient subsequently developed a deep surgical site infection caused by MDR A. baumannii, resistant to multiple antibiotic classes. This case underscores the importance of culture-guided antibiotic selection, a role for the use of local antibiotic therapy. It also highlights therapeutic challenges in managing MDR infections in orthopedic surgery and the need for collaboration with the microbiology team.