Recurrence Screening of Undifferentiated Pleomorphic Sarcoma with Giant Cells of the Breast.

BACKGROUND

Undifferentiated pleomorphic sarcoma (UPS) of the breast is a rare mesenchymal tumor that is not commonly encountered in clinical settings. Given its high recurrence rate, close monitoring, and follow-up are strongly recommended.

METHODS

In this case, the recurrence of UPS with giant cells of the breast was screened through ultrasound imaging and tumor marker tests, including CA 15-3 and CA 72-4.

RESULTS

Following recurrence, the patient achieved partial clinical remission after six cycles of epirubicin-based adjuvant chemotherapy. In accordance with the patient's preference, a left mastectomy was performed. Postoperatively, the patient's condition stabilized, with a smooth and satisfactory recovery.

CONCLUSIONS

This case demonstrates that the combined evaluation of abnormal carbohydrate antigen expression and ultrasound features can enhance the diagnostic accuracy of suspected recurrent nodules following surgery for UPS of the breast.