Congenital hyperinsulinism and neonatal diabetes mellitus.

This special edition of the Reviews in Metabolic and Endocrine Disorders provides a state of the state update on congenital hyperinsulinism and neonatal diabetes mellitus. Understanding the molecular mechanisms of these two disorders has provided fundamental insights into pancreatic beta-cell physiology. This knowledge has also had a significant impact on our clinical approach to patients with these two disorders and fundamentally changed patient management.