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American journal of infection control · 2026

Safety window and quality control of delayed reprocessing for flexible endoscopes.

СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Chen Li-Na, Qian Jia, Li Wen-Qing, Gu Qing

Аннотация

BACKGROUND: Delays between bedside pre-cleaning and manual reprocessing may impair endoscope cleaning, but acceptable delay intervals remain unclear.

METHODS: Six types of endoscopes were contaminated with sheep blood, pre-cleaned, and manually cleaned after type-specific delays. Gastrointestinal endoscopes contaminated with sheep blood, fluorescent marker, and Escherichia coli were pre-cleaned with moisturizing or non-moisturizing enzymatic detergent and reprocessed after delays of 3, 8, or 24 hours. Protein residue, microbial recovery, borescope findings, and fluorescence were assessed at 3 stages: before manual cleaning, after manual cleaning, and after automated endoscope reprocessor processing.

RESULTS: Cleaning pass rates declined when delays exceeded 2 hours for gastrointestinal endoscopes, therapeutic gastrointestinal endoscopes, and colonoscopes. Duodenoscopes were particularly affected, with pass rates decreasing to 20% at 2 hours and 0% at 2.5 hours. At an 8-hour delay, moisturizing detergent provided better microbial control than non-moisturizing detergent. All gastrointestinal endoscopes met the microbiological criterion after the complete automated endoscope reprocessor cycle.

DISCUSSION: Delayed reprocessing primarily impaired manual cleaning, particularly in structurally complex endoscopes.

CONCLUSIONS: The findings support prompt manual cleaning and moisture retention when delays are unavoidable. The delay thresholds observed in this experimental model require clinical validation.

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

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